A review of topical and systemic nutrients in the management of melasma Dr Laurena Law BMED (Newcastle) DFM (HKCFP) Dip in Practical Dermatology (cardiff) P Dip ComPsychMed (Hong Kong) Melasma is a complex pigmentary condition Melasma is a complex pigmentary condition with a higher prevalence of around 90% occurs in females and dark skin types. Multiple etiologies including light exposure, hormonal influences (such as pregnancy or oral contraceptive pill use), family history and oxidative stress have been implicated in the pathogenesis of this disorder. When melasma occurs during pregnancy, it is called chloasma or ‘mask of pregnancy.’ It often fades gradually after delivert, but may remain for years or permanently. Histology shows increased melanosomes, solar elastosis, dermal blood vessels and perivascular lymphohistiocytic infiltrates. Various treatment modalities including, chemical peels, topical lightening agents, lasers/ light-based devices and or...
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