Novel Treatment of Melasma Patients with Oral Tranexamic Acid: a case series I. Jane Hidajat , 1,2 Veronica 1 1 Department of Dermatovenereology, School of Medicine and Health Sciences Atma Jaya Catholic University of Indonesia, 2 Youth & Beauty Clinic Jakarta ABSTRACT Introduction : Melasma is a common, relapsing, acquired, symmetrical facial hypermelanosis, and had been recognized for centuries as it was initially reported by Hippocrates . The treatment of melasma is still challenging, various modalities from topical treatment to laser/light therapy have been developed, without satisfactory results, due to side effects and recurrences. Recently, there is a promising novel therapy in treating melasma with tranexamic acid (TA). It can be administered through topical, intradermal, microneedling, and oral routes. The response to oral tranexamic acid was reported to be more efficacious than other administration routes. Here we report the efficacy and s...
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